Vancomycin Exposure Predicts Early Clinical Response in Complicated Skin and Soft Tissue Infections Caused by Methicillin-Resistant Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Early appropriate parenteral antimicrobial treatment of complicated skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus.
BACKGROUND Complicated skin and soft tissue infections (cSSTIs) are a major clinical problem, in part because of the increasing resistance of infecting bacteria to our current antibiotic therapies. Prompt appropriate treatment of infections in hospitalized patients reduces the mortality rate. Furthermore, appropriate and timely antibiotic therapy improves outcomes for cSSTIs caused by methicill...
متن کاملSkin and soft-tissue infections caused by community-acquired methicillin-resistant Staphylococcus aureus.
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection has become epidemic. Skin and soft-tissue infections (SSTIs) are the most frequent forms of the disease. Obtainment of culture specimens is important for documentation of the presence of MRSA and for susceptibility testing to guide therapy. Purulent lesions should be drained whenever possible. In areas where communi...
متن کاملSkin and Soft Tissue Infections Caused by Methicillin-Resistant Staphylococcus aureus USA300 Clone
BACKGROUND Accurate diagnosis and initial management of skin and soft tissue infections (SSTIs) are essential to providing adequate care to patients. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of SSTIs, and surgeons and other healthcare providers should assess these infections carefully to improve patient outcomes. METHODS Review of the pertinent literatur...
متن کاملClinical importance of purulence in methicillin-resistant Staphylococcus aureus skin and soft tissue infections.
BACKGROUND The so-called community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains are more frequently susceptible to non-ss-lactam antibiotics (including clindamycin) than health care-associated MRSA strains. We assessed whether predictive clinical characteristics of presumptive MRSA infections can be identified to guide choice of empiric antibiotic therapy. METHODS A c...
متن کاملClinical Aspects of Infections Caused by Methicillin-resistant Staphylococcus Aureus
Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial infections. Clinical presentation of infections is determined by the way of the acquisition of the pathogen then by virulence factors itself. In the intensive care units MRSA causes blood stream infections (BSI) associated with the use of venous lines as well as ventilator-associated pneumonia (VAP). MRSA is ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2015
ISSN: 2328-8957
DOI: 10.1093/ofid/ofv133.517